Central serous retinopathy (CSR), also known as central serous chorioretinopathy (CSC or CSCR), is an eye disease where fluid builds up under the retina, causing distorted vision. In CSC, the fluid leakage comes from a layer of tissue under the retina, called the choroid. And that buildup of fluid can come from small breaks in a layer of cells called the retinal pigment epithelium (RPE). This causes a small detachment under the retina, resulting in a blurred or grey spot in the central field of vision. CSC typically affects one eye at a time but can affect both. It is seen most often in white males, age 20 to 50. While the cause of this disease is unknown, stress and corticosteroid use can make it worse.